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Showing 1 to 12 of 134 entries
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Interleukin-1 in cardiac injury, repair, and remodeling: pathophysiologic and translational concepts.

Discoveries (Craiova, Romania)

Frangogiannis NG.
PMID: 26273700
Discoveries (Craiova). 2015 Jan-Mar;3(1). doi: 10.15190/d.2015.33.

In the infarcted myocardium, necrotic cardiomyocytes release danger signals activating an intense inflammatory reaction that serves to clear the wound from dead cells and matrix debris, but may also extend injury. A growing body of evidence suggests an important...

An updated h-index measures both the primary and total scientific output of a researcher.

Discoveries (Craiova, Romania)

Bucur O, Almasan A, Zubarev R, Friedman M, Nicolson GL, Sumazin P, Leabu M, Nikolajczyk BS, Avram D, Kunej T, Calin GA, Godwin AK, Adami HO, Zaphiropoulos PG, Richardson DR, Schmitt-Ulms G, Westerblad H, Keniry M, Grau GE, Carbonetto S, Stan RV, Popa-Wagner A, Takhar K, Baron BW, Galardy PJ, Yang F, Data D, Fadare O, Yeo KJ, Gabreanu GR, Andrei S, Soare GR, Nelson MA, Liehn EA.
PMID: 26504901
Discoveries (Craiova). 2015 Jul-Sep;3(3). doi: 10.15190/d.2015.42. Epub 2015 Sep 30.

The growing interest in scientometry stems from ethical concerns related to the proper evaluation of scientific contributions of an author working in a hard science. In the absence of a consensus, institutions may use arbitrary methods for evaluating scientists...

Macro Photography with Lightsheet Illumination Enables Whole Expanded Brain Imaging with Single-cell Resolution.

Discoveries (Craiova, Romania)

Lee CM, Tian X, Tsao C, Chen P, Huang TN, Hsueh YP, Chen BC.
PMID: 34849398
Discoveries (Craiova). 2021 Aug 04;9(3):e133. doi: 10.15190/d.2021.12. eCollection 2021.

Macro photography allows direct visualization of the enlarged whole mouse brain by a combination of lightsheet illumination and expansion microscopy with single-cell resolution.  Taking advantage of the long working distance of a camera lens, we imaged a 3.7 cm...

Increased QRS duration and dispersion are associated with mechanical dyssynchrony in patients with permanent right ventricular apical pacing.

Discoveries (Craiova, Romania)

Chávez-González E, Nodarse-Concepción A, Donoiu I, Rodríguez-González F, Puerta RC, Elizundia JMC, Peña GP, Rodríguez-Jiménez AE.
PMID: 34849395
Discoveries (Craiova). 2021 Jun 26;9(2):e128. doi: 10.15190/d.2021.7. eCollection 2021.

BACKGROUND: Permanent right ventricular apical pacing may have negative effects on ventricular function and contribute to development of heart failure. We aimed to assess intra- and interventricular mechanical dyssynchrony in patients with permanent right ventricular apical pacing, and to...

Information technology-based joint preoperative assessment, risk stratification and its impact on patient management, perioperative outcome, and cost.

Discoveries (Craiova, Romania)

Karim HMR, Singha SK, Neema PK, Baruah TD, Ray R, Mohanty D, Siddiqui MS, Nanda R, Bodhey NK.
PMID: 34849397
Discoveries (Craiova). 2021 Jun 30;9(2):e130. doi: 10.15190/d.2021.9. eCollection 2021.

BACKGROUND:  Despite negative recommendations, routine preoperative testing practice is nearly universal. Our aim is to bring the healthcare providers on one platform by using information-technology based preanaesthetic assessment and evaluate the routine preoperative testing's impact on patient outcome and...

High mortality co-infections of COVID-19 patients: mucormycosis and other fungal infections.

Discoveries (Craiova, Romania)

Bhatt K, Agolli A, Patel MH, Garimella R, Devi M, Garcia E, Amin H, Domingue C, Guerra Del Castillo R, Sanchez-Gonzalez M.
PMID: 34036149
Discoveries (Craiova). 2021 Mar 31;9(1):e126. doi: 10.15190/d.2021.5.

Severe COVID-19 disease is associated with an increase in pro-inflammatory markers, such as IL-1, IL-6, and tumor necrosis alpha, less CD4 interferon-gamma expression, and fewer CD4 and CD8 cells, which increase the susceptibility to bacterial and fungal infections. One...

COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus.

Discoveries (Craiova, Romania)

Jan H, Faisal S, Khan A, Khan S, Usman H, Liaqat R, Shah SA.
PMID: 32377559
Discoveries (Craiova). 2020 Apr 26;8(2):e108. doi: 10.15190/d.2020.5.

An epidemic of extreme respiratory deterrence, pneumonia and shortness of breath, the SARS-CoV-2 viral infection began in Wuhan, Hubei Province, China in December 2019, and rapidly spread across China and beyond, with human to human transmission. On February 12,...

A CRISPR View of Biological Mechanisms.

Discoveries (Craiova, Romania)

Martinez E, Sanchez L, Vazquez N, Marks R, Cedillo R, Respondek C, Holguin M, Persans MW, Keniry M.
PMID: 32309588
Discoveries (Craiova). 2016 Dec 31;4(4):e69. doi: 10.15190/d.2016.16.

A decade ago, only six manuscripts would be found on a PubMed search for "CRISPR," compared to 2,011 manuscripts in 2016. The purpose of this review is to discuss this emergent technology that has revolutionized molecular biological research in...

Fusion Pore: A Curious Case of Rediscovering Science.

Discoveries (Craiova, Romania)

Mitagvaria NP.
PMID: 32309591
Discoveries (Craiova). 2017 Apr 16;5(2):e73. doi: 10.15190/d.2017.3.

No abstract available.

Bacterial RNA as a signal to eukaryotic cells as part of the infection process.

Discoveries (Craiova, Romania)

Simonov D, Swift S, Blenkiron C, Phillips AR.
PMID: 32309589
Discoveries (Craiova). 2016 Dec 31;4(4):e70. doi: 10.15190/d.2016.17.

The discovery of regulatory RNA has identified an underappreciated area for microbial subversion of the host. There is increasing evidence that RNA can be delivered from bacteria to host cells associated with membrane vesicles or by direct release from...

Update of the 1972 Singer-Nicolson Fluid-Mosaic Model of Membrane Structure.

Discoveries (Craiova, Romania)

Nicolson GL.
PMID: 32309537
Discoveries (Craiova). 2013 Dec 31;1(1):e3. doi: 10.15190/d.2013.3.

The Fluid-Mosaic Membrane Model of cell membrane structure was based on thermodynamic principals and the available data on component lateral mobility within the membrane plane [Singer SJ, Nicolson GL. The Fluid Mosaic Model of the structure of cell membranes....

Quantitative dynamics of VE-cadherin at endothelial cell junctions at a glance: basic requirements and current concepts.

Discoveries (Craiova, Romania)

Seebach J, Cao J, Schnittler HJ.
PMID: 32309583
Discoveries (Craiova). 2016 Aug 24;4(3):e63. doi: 10.15190/d.2016.10.

Intercellular junctions of the vascular endothelium are dynamic structures that display a high degree of plasticity, which is required to contribute to their regulation of many physiological and pathological processes including monolayer integrity, barrier function, wound healing and angiogenesis....

Showing 1 to 12 of 134 entries